Generic drug of the Therapeutic class: Metabolism and nutrition
Active ingredients: Cholecalciferol
what is Zymad ?
This medication is usually prescribed for:
- Vitamin D deficiency
what is Zymad medication used for and indication?
It is indicated for the treatment and / or prevention of vitamin D deficiency.
Presentation (s) available for Zymad 200,000 IU
1 ampoule (s) in 2 ml amber glass
| FEATURE | DESCRIPTION |
| Pharmaceutical class | vitamins |
| Active substance (s) | for one ampoule: cholecalciferol (200,000 IU) |
| General medicine | no |
| Pharmaceutical form | drinkable solution |
| Route (s) of administration | oral |
| Social security reimbursement rate | 65% |
| Laboratory (s) | ROTTAPHARM SARL |
| Conditions of issue | available by simple prescription |
Zymad Dosage
Dosage, Frequency of administration and Duration of treatment
Vitamin deficiency in children
Prophylaxis
Its implementation is:
Imperative in all infants from 0 to 18 months then during the winter period in children up to the age of 5 (ministerial circulars of February 21, 1963 and January 6, 1971),
Recommended for children and adolescents when living conditions include:
- insufficient exposure to the sun,
- a diet low in vitamin D.
Premature:
It is preferable to administer daily doses in drops
From 0 to 18 months:
- Without milk enriched with vitamin D or in children with pigmented skin: 1 vial every 6 months.
From 18 months to the end of adolescence:
- Without digestive pathology: 1 ampoule at the beginning of winter
- With digestive pathology or receiving anti-convulsants: 1 ampoule every 3 months.
Treatment
- 1 ampoule, renewable once for 6 months, then resume the usual prophylaxis to prevent relapses. Do not exceed a total dose of 600,000 IU / year.
Vitamin deficiency in adults and the elderly
Prophylaxis
- Elderly subject: 1 ampoule every 6 months.
- Adult at risk of deficiency (digestive pathology, in an institution, anti-convulsant treatment, etc.): 1 ampoule every 6 months.
Treatment
- 1 ampoule renewable once or twice over 6 months, then resume the usual prophylaxis to prevent relapses. Do not exceed a total dose of 600,000 IU / year.
Zymad Contraindications
Never take ZYMAD 200,000 IU, oral solution in an ampoule in the event of:
- known allergy to vitamin D or any of the other constituents;
- hypercalcemia (excess calcium in the blood), hypercalciuria (excess calcium in the urine), calcium lithiasis (kidney stones).
How To Take Zymad ?
Method and / or route (s) of administration
Oral route.
how does Zymad work?
Vitamin D is absorbed in the small intestine passively, then reaches the general circulation by lymphatic route, incorporated into chylomicrons.
After absorption, it binds to a specific carrier protein and is transported to the liver where it is converted into 25-hydroxyvitamin D. This in turn binds to the same carrier protein and is transported to the kidneys where it is. transformed into its active form, 1,25-dihydroxyvitamin D.
Its essential storage sites are adipose tissue, muscles, but also blood. The 25-hydroxyvitamin D bound to its carrier protein is the major circulating reserve form of vitamin D. Its half-life in the blood is 15 to 40 days.
The elimination of vitamin D and its metabolites occurs via the faeces, in unprocessed form or in water-soluble form (calcitroic acid, glycuroconjugate derivatives).
How To Store Zymad ?
- Keep this medication out of the sight and reach of children.
- Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month.
- Store at a temperature not exceeding 25 ° C.
- Keep the ampoule in the outer carton in order to protect from light.
- Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
Zymad Side Effects
Like all medicines, ZYMAD 200,000 IU oral solution in ampoule can cause side effects, although not everybody gets them.
- Skin and subcutaneous tissue disorders: pruritus, rash, erythema, edema.
If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
Zymad Interactions
Combinations subject to precautions for use
+ Enzyme-inducing anticonvulsants
- Decrease in vitamin D concentrations more marked than without treatment with inducers.
- Determination of vitamin D concentrations and supplementation if necessary.
+ Rifampicin
- Decrease in vitamin D concentrations more marked than without treatment with rifampicin.
- Determination of vitamin D concentrations and supplementation if necessary.
Associations to take into account
+ Orlistat:
- Decreased absorption of vitamin D.
Effects on ability to Drive and use machines
- Not applicable.
- Not applicable.
- Not applicable.
- Not applicable.
Warnings and Precautions
To avoid overdose, consider the total doses of vitamin D when combined with treatment already contain this vitamin or if milk using supplemented with vitamin D.
In indications requiring repeated doses, monitor urinary calcium and serum calcium and stop the intake of vitamin D if calcium levels exceed 106 mg / l (2.65 mmol / l) or the calcium exceeds 300 mg / 24 h in adults or 4-6 mg / kg / day in children.
PREGNANCY & BREAST-FEEDING & FERTILITY
Pregnancy
- If needed, vitamin D can be prescribed during pregnancy. ZYMAD 200,000 IU is not a suitable strength for pregnant women.
- Ask your doctor or pharmacist for advice before taking any medicine.
Feeding with milk
- If needed, vitamin D can be prescribed during breastfeeding. However, this supplementation does not replace the administration of vitamin D in the newborn.
- Ask your doctor or pharmacist for advice before taking any medicine.
What happens if I overdose from Zymad ?
f you take more ZYMAD 200,000 IU, oral solution in ampoule than you should:
Immediately consult your doctor or pharmacist.
The clinical signs of an overdose are:
- · Headache, fatigue, loss of appetite, weight loss, stunted growth;
- · Nausea, vomiting;
- Profuse urine, intense thirst, dehydration;
- · Kidney stones, calcification of tissues, especially kidney and vessels;
- · Renal failure (failure of kidney function).
The biological signs of an overdose are:
- · Increase in calcium levels in the blood and urine and increased phosphorus levels in the blood and urine, low concentration and high parathyroid hormone 25-hydroxyvitamin D .
- In the event of an overdose, treatment should be stopped, calcium intake (dairy) limited and your doctor should be consulted.
What should I do if I miss a dose?
If you forget to take ZYMAD 200,000 IU, oral solution in ampoule
- N o not take a double dose to make up the dose you missed.
What happens if you stop taking Zymad ?
- Not applicable.
- Not applicable.
- Not applicable.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse for more information.
What is Forms and Composition ?
Appearance and shape
- Oral solution in ampoule.
- 2 ml in 5 ml ampoule (type III brown glass) with breakable tip. Box of 1.
Other shapes
- ZYMAD 50,000 IU Oral solution box of 1 ampoule of 2 ml
- ZYMAD 80,000 IU Oral solution box of 1 ampoule of 2 ml
- ZYMAD 10,000 IU / ml, oral solution in drops, box of 1 vial (+ dropper) of 10 ml.
Composition
| Active ingredient | Drinkable solution |
|---|---|
| Cholecalciferol | 200,000 IU * |
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
- Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
- General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
- For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
- It treats possible side effects and drug interactions that require attention and its effect on continuous use.
- The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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